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Merck

PHR1012

Supelco

对羟基苯甲酸甲酯

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-羟基苯甲酸甲酯, 对羟基苯甲酸甲酯, 对羟苯甲酸甲酯, 尼泊金甲酯

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1 G
$152.00
10 G
$837.00

$152.00


预计发货时间2025年2月03日详情


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1 G
$152.00
10 G
$837.00

About This Item

线性分子式:
HOC6H4CO2CH3
CAS号:
分子量:
152.15
Beilstein:
509801
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
酶號碼:
E218
NACRES:
NA.24

$152.00


预计发货时间2025年2月03日详情


获取大包装报价

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. M1650000
traceable to USP 1432005

API 家族

parabens

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

125-128 °C (lit.)

應用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI 密鑰

LXCFILQKKLGQFO-UHFFFAOYSA-N

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一般說明

对羟基苯甲酸甲酯是一种抗真菌剂和抗菌剂,广泛用于化妆品、药品、食品和饮料领域。[1]
药物二级标准品CRM,为制药行业QC实验室及生产质量控制和研发,提供了一种方便、高性价比且符合相关法规的替代方案。

應用

对羟基苯甲酸甲酯可用作药物参考标准品,用于通过反相序贯进样色谱法(SIC)[2]和高效液相色谱技术量化制药配方中的分析物。[3]
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析報告

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他說明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

腳註

要查看该材料的分析证书示例,请在下面的栏位中输入LRAC0280。这只是一个示例证书,可能不是您收到的批次。

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在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析(使用数字化外标)。可查看该物质的NMR谱图,只需点击几次鼠标,就能进行在线样品比对。欢迎点击了解更多,开启免费试用之旅。

象形圖

Environment

危險聲明

防範說明

危險分類

Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

334.4 °F

閃點(°C)

168 °C


分析证书(COA)

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A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation
Kokoletsi XM, et al.
Journal of Pharmaceutical and Biomedical Analysis, 38(4), 763-767 (2005)
Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column
Satinsky D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(2), 287-293 (2006)
Simultaneous determination of methylparaben, propylparaben, hydrocortisone acetate and its degradation products in a topical cream by RP-HPLC.
Hajkova R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 32(4-5), 921-927 (2003)
K Kannathasan et al.
Acta tropica, 120(1-2), 115-118 (2011-07-19)
The vector-borne diseases caused by mosquitoes are one of the major health problems in many countries especially in tropical and sub-tropical countries. The resistance of mosquitoes to synthetic chemicals and environmental toxicity created by the chemicals raised the demand for
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

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