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47673

Sigma-Aldrich

甲醛 溶液

tested according to Ph. Eur.

别名:

35% 甲醛溶液, 福尔马林

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1 L
$99.20

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1 L
$99.20

About This Item

线性分子式:
HCHO
CAS号:
50-00-0
分子量:
30.03
Beilstein:
1209228
MDL编号:
MFCD00003274
UNSPSC代码:
12352114
PubChem化学物质编号:
329757334
NACRES:
NA.25

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Agency

USP/NF
tested according to Ph. Eur.

质量水平

200

蒸汽密度

1.03 (vs air)

蒸汽压

52 mmHg ( 37 °C)

表单

liquid

自燃温度

572 °F

包含

9.0-15.0 % (v/v) methanol as stabilizer

浓度

25-50%

溶解性

water: soluble

密度

1.09 g/mL at 25 °C (lit.)

适用性

suitable for manufacturing use (Laboratory chemicals)

SMILES字符串

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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应用

在流式细胞术中，甲醛溶液已被用于固定标记的细胞。[1]

生化/生理作用

甲醛是最简单的醛，其可使RNA的双螺旋区域变性并将多核苷酸转化为无规卷曲。[2] 它是一种遗传毒性物质，可显著诱导DNA-蛋白质交联（DPC）、姐妹染色单体交换、微核形成并导致细胞毒性。[3] 它还在大鼠的鼻上皮中诱导肿瘤并且被认为是人类致癌物。

注意

储存时可能变混浊

警示用语：

Danger

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

靶器官

Eyes,Central nervous system, Respiratory system

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

133.0 °F - closed cup

闪点(°C)

56.11 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM5411
BCCM4820
BCCL7378
BCCL8065
BCCL5543

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J L Wilson et al.
Journal of immunology (Baltimore, Md. : 1950), 163(12), 6365-6370 (1999-12-10)
NK cells have the capacity to spontaneously kill tumor cell lines, in particular cell lines of hemopoietic origin. In contrast, they do not generally kill nontransformed autologous cells. However, here we demonstrate that short-term activated polyclonal human NK cells, as
O Merk et al.
Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.
H Boedtker
Journal of molecular biology, 35(1), 61-70 (1968-07-14)
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
Stephanie Belloc et al.
Fertility and sterility, 101(6), 1588-1593 (2014-04-03)
To evaluate sperm DNA fragmentation in normozoospermic male partners of couples undergoing infertility evaluation. Retrospective cohort study. Clinical andrology laboratory. A total of 1,974 consecutive normozoospermic men selected from a larger cohort of 4,345 consecutive, nonazoospermic men presenting for infertility
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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