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Merck

HT501128

Sigma-Aldrich

甲醛溶液,中性缓冲,10%

histological tissue fixative

别名:

甲醛

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About This Item

MDL號碼:
分類程式碼代碼:
12352114
PubChem物質ID:
NACRES:
NA.47

生物源

synthetic

品質等級

濃度

10% formalin (approx. 4% formaldehyde)

顏色

colorless

pH值

6.90-7.10

密度

1.080 g/cm3

應用

hematology
histology

儲存溫度

room temp

InChI

1S/CH2O/c1-2/h1H2

InChI 密鑰

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般說明

10%中性缓冲的甲醛(NBF)是全世界范围内用于光学显微镜最常使用的固定剂,并且也是一种较为宽容的固定剂。10% NBF很适合于高通量的实验室,并只需要一段相对短的固定时间,但也可用于组织的长期储存。甲醛固定被视为在醛和蛋白之间形成的,并生成凝胶,从而在它们的体内关系上保留细胞性组成。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。

應用

10%甲醛中性缓冲溶液已用于3T3-L1前脂肪细胞系及小鼠胚胎成纤维细胞分化至脂肪细胞的油红-o染色。它已用于兔眼及糖尿病大鼠肠的组织学分析。
10%甲醛中性缓冲溶液已被用作一种常用的通用组织固定剂用于对组织进行固定。
常用的通用组织学固定剂。

外觀

中性缓冲的溶液

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

水污染物質分類(WGK)

WGK 3

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Jonathan C J Wei et al.
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Emerging micro-scale medical devices are showing promise, whether in delivering drugs or extracting diagnostic biomarkers from skin. In progressing these devices through animal models towards clinical products, understanding the mechanical properties and skin tissue structure with which they interact will
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Nu?o K, et al.
Journal of functional foods, 5(1) (2013)
Recapitulating spatiotemporal tumor heterogeneity in vitro through engineered breast cancer microtissues.
Mazio c, et al.
Acta Biomaterialia, 73, 236-249 (2018)
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.
Hassler M R, et al.
Nucleic Acids Research, 46(5), 2185-2196 (2018)
A S Byrd et al.
Scientific reports, 9(1), 12207-12207 (2019-08-23)
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder characterized by painful nodules, sinus tracts, and scars occurring predominantly in intertriginous regions. The prevalence of HS is currently 0.053-4%, with a predominance in African-American women and has been linked to low

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