487950

NOC-5

A nitric oxide (NO) donor.

• 别名: NOC-5, 3-[2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino]-1-propanamine
• 经验公式（希尔记法）: C₆H₁₆N₄O₂
• CAS号: 146724-82-5
• 分子量: 176.22
• MDL號碼: MFCD00274389
• 分類程式碼代碼: 12352200

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic); protect from light
• 顏色: white
• 溶解度: 0.1 M NaOH: soluble; water: soluble
• 運輸包裝: ambient
• 儲存溫度: −20°C
• InChI: 1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,12H,3-5,7H2,1-2H3
• InChI 密鑰: WEHZRCACNLQADC-UHFFFAOYSA-N

说明

一般說明

A nitric oxide (NO) donor. A stable NO-amine complex that can release two equivalents of NO spontaneously in solution under physiological conditions without a cofactor. Half-life (t_½) of NO release is 93 min (PBS, pH 7.4, 22°C).

A nitric oxide (NO) donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Half-life (t_½) in PBS, pH 7.4 is 93 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0).

生化／生理作用

Cell permeable: no

Primary Target
A nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

重構

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

其他說明

Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02
• 訊號詞: Danger
• 危險聲明: H242
• 防範說明: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危險分類: Self-react. C
• 儲存類別代碼: 5.2 - Organic peroxides and self-reacting hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable