369075

Guanidine Hydrochloride

ULTROL^® Grade, ≥99% (titration), protein denaturant for purification of proteins, nucleic acids, and mRNA

• 别名: Guanidinium chloride
• 经验公式（希尔记法）: CH₅N₃ · xHCl
• CAS号: 50-01-1
• 分子量: 59.07 (free base basis)
• MDL號碼: MFCD00013026
• 分類程式碼代碼: 12352107
• NACRES: NA.25

属性

• 品質等級: 100
• 化驗: ≥99% (titration)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 顏色: white
• 溶解度: ethanol: soluble; water: soluble
• 運輸包裝: ambient
• 儲存溫度: 15-25°C
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• InChI 密鑰: PJJJBBJSCAKJQF-UHFFFAOYSA-N

说明

一般說明

A powerful protein denaturant that is widely used in the purification of proteins, nucleic acids, and mRNA. It is used in a variety of applications, including sequencing, molecular weight determinations, and as a solubilizing agent for electrophoresis.

Absorbance (6.0 M, H₂O): <0.2 at 230 nm; <0.03 at 260 nm.

應用

• Revealing the Roles of Guanidine Hydrochloride Ionic Liquid in Ion Inhibition and Defects Passivation for Efficient and Stable Perovskites Solar Cells: Discusses how guanidine hydrochloride ionic liquid enhances the efficiency and stability of perovskite solar cells by ion inhibition and defect passivation (Saeed A et al., 2024).


• N-Fluorosulfonyl Guanidine: An Entry to N-Guanyl Sulfamides and Sulfamates: Investigates the use of N-fluorosulfonyl guanidine for synthesizing N-guanyl sulfamides and sulfamates, showcasing its potential in chemical synthesis and material science (Wang W et al., 2024).


• Efficient extraction of lignin from moso bamboo by microwave-assisted ternary deep eutectic solvent pretreatment for enhanced enzymatic hydrolysis: Explores the role of guanidine hydrochloride in enhancing the enzymatic hydrolysis of lignin extracted from moso bamboo using a microwave-assisted deep eutectic solvent method (Feng Y et al., 2024).


• Computational Enzyme Redesign Enhances Tolerance to Denaturants for Peptide C-Terminal Amidation: Details how computational redesign of enzymes, involving guanidine hydrochloride, can enhance their tolerance to denaturants, improving the efficiency of peptide C-terminal amidation processes (Zhu T et al., 2024).


• Parasite Burden of Trypanosoma cruzi in Whole Blood and Buffy Coat Determined by Real-Time PCR in Individuals with Chronic Chagas Disease: Describes the use of guanidine hydrochloride in real-time PCR processes to quantify the parasite burden in blood samples from individuals with Chagas disease, demonstrating its utility in enhancing diagnostic assays (Liempi D et al., 2024).

警告

Toxicity: Harmful (C)

其他說明

Bastiras, S., and Wallace, J.C. 1992. Biochemistry31, 9304.
Plaza del Pino, I.M., et al. 1992. Biochemistry31, 11196.
Steinman, H., et al. 1974. J. Biol. Chem.249, 7326.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H332,H315,H319
• 防範說明: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable