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product name
羰基氰化m-氯苯腙, Protonophore. Uncoupling agent for oxidative phosphorylation that inhibits mitochondrial function. Approximately 100 times more effective than 2,4-dinitrophenol.
品質等級
化驗
≥95% (HPLC)
形狀
solid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
顏色
yellow
溶解度
ethanol: 1 mg/mL
DMSO: 5 mg/mL
運輸包裝
ambient
儲存溫度
2-8°C
InChI
1S/C9H5ClN4/c10-7-2-1-3-8(4-7)13-14-9(5-11)6-12/h1-4,13H
InChI 密鑰
UGTJLJZQQFGTJD-UHFFFAOYSA-N
一般說明
质子体。用于氧化磷酸化的解偶联剂，可抑制线粒体功能。比 2,4-二硝基苯酚有效约 100 倍。以高亲和力结合细胞色素 C 氧化酶（Kd = 270 nM）。抑制运输过程并抑制生长。
质子体。用于氧化磷酸化的解偶联剂，可抑制线粒体功能。比 2,4-二硝基苯酚有效约 100 倍。以高亲和力结合细胞色素 c 氧化酶（Kd = 270 nM）。抑制运输过程并抑制生长。
生化／生理作用
与细胞色素 c 氧化酶结合的 Kd = 270 nM
主靶
细胞色素 c 氧化酶
细胞色素 c 氧化酶
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：有害（C）
重構
在重悬后存放于冰箱（4°C）。储备液可在4°C最长稳定1个月。
其他說明
Bona, M., et al. 1993.Gen.Physiol.Biophys.12, 533.
Heytler, P.G., and Prichard, W.W.1962.Biochem.Biophys.Res. Commun.7, 272.
Heytler, P.G., and Prichard, W.W.1962.Biochem.Biophys.Res. Commun.7, 272.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
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