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product name
羰基氰化物 4-（三氟甲氧基）苯腙, ≥98% (TLC), powder
品質等級
化驗
≥98% (TLC)
形狀
powder
顏色
yellow
mp
174-175 °C (dec.) (lit.)
溶解度
95% ethanol: soluble
儲存溫度
2-8°C
SMILES 字串
FC(F)(F)Oc1ccc(N\N=C(/C#N)C#N)cc1
InChI
1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H
InChI 密鑰
BMZRVOVNUMQTIN-UHFFFAOYSA-N
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一般說明
FCCP是一种质子载体（H+ 离子载体），也是线粒体氧化磷酸化的解偶联剂。它能够促使质膜和线粒体膜去极化。FCCP可影响细胞钙离子参与的各种活动。它还能抑制K+ 背景电流和诱导小量内向电流，降低0.1单位的pH，以及诱导胞内[Na+]升高。FCCP能刺激Mg2+-ATP酶活性，抑制β-淀粉样蛋白生成，以及模拟选择性谷氨酸激动剂N-甲基-D-天冬氨酸(NMDA)对线粒体超氧化物产生的影响。
應用
碳酰腈4-三氟甲氧基苯腙(FCCP)可作为细胞培养的解偶联剂：用于研究其对产热脂肪细胞的影响，用于研究其对小鼠线粒体β-氧化的作用，用于研究其对小鼠骨髓来源树突状细胞的代谢影响。
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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