跳转至内容
Merck

1.20091

SAFC

二氧化硅

EMPROVE® ESSENTIAL, Ph. Eur., NF

制药生产

别名:

二氧化硅

登录查看公司和协议定价


About This Item

线性分子式:
SiO2
CAS号:
分子量:
60.08
MDL號碼:
分類程式碼代碼:
12352201
价格与库存信息目前不能提供

agency

NF
Ph. Eur.

品質等級

產品線

EMPROVE® ESSENTIAL

形狀

fine powder

粒徑

17-25 μm (d50)

bp

2230 °C (lit.)

mp

>1600 °C (lit.)
1710 °C

應用

pharmaceutical
pharmaceutical
solid formulation
solubility enhancement

儲存溫度

2-30°C

SMILES 字串

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI 密鑰

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Parteck® SLC excipient is an innovative silica drug carrier that enhances drug solubility thanks to its unique surface structure, which can stabilize the amorphous state. This is especially relevant for poor glass forming APIs, which can be difficult to stabilize with other formulation technologies. Parteck® SLC is also emerging as a first-in-class excipient to reduce the risk of unstable polymorphism and particle properties in drug development. In this application, Parteck® SLC can homogenize both properties in a template-based formulation approach, with robust and reliable results.

特點和優勢

  • Solubility enhancement of APIs
  • Unparalleled stabilization of the amorphous solid state
  • Unique pore structure (6 nm diameter) and a very high surface area (500 m²/g)
  • Perfect fit to stabilize poor glass former molecules
  • Platform approach to manage API particle and polymorph variation
  • No specific equipment/extra capital invest needed to stabilize the amorphous form of APIs
  • High-end application support

包裝

1200910300 // Wide necked plastic bottle in corrugated box
1200911000 // Wide necked plastic bottle in corrugated box
1200919025 // Standard PE bag in PE square drum

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


什么是Emprove®程序?

Emprove® 程序是提供我们过滤器、一次性组件、制药原料和初始材料的全面而详尽文档的系统。

了解更多权益。 Emprove® 程序订阅所提供的好处
为何这些文件不可用?
Emprove®档案所包含的信息旨在为药品生产商的注册和风险评估活动提供支持,其中有一些机密信息。如果您想访问这些信息,请联系我们

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

商品

Our overview of API solubility and dissolution enhancement methods can help you decide between the many options to take during formulation.

Questions

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门