1.00419

Parteck^® M 200（甘露醇）

EMPROVE^® ESSENTIAL, Ph. Eur., ChP, JP, USP, E 421

• 别名: D-甘露醇
• 经验公式（希尔记法）: C₆H₁₄O₆
• CAS号: 69-65-8
• 分子量: 182.17
• MDL號碼: MFCD00064287
• 分類程式碼代碼: 12352201
• 酶號碼: E421
• 酶委員會索引編號: 200-711-8

属性

• agency: BP; ChP; JP; Ph. Eur.; USP
• 品質等級: 500
• 產品線: EMPROVE^® ESSENTIAL
• 形狀: fine powder
• 自燃溫度: 410 °C
• 品質: E 421
• 粒徑: (see specification)
• bp: 290-295 °C/4 hPa
• mp: 164-169 °C
• 溶解度: 213 g/L
• 應用: liquid formulation; pharmaceutical; solid formulation
• 儲存溫度: 2-25°C
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2
• InChI 密鑰: FBPFZTCFMRRESA-UHFFFAOYSA-N

说明

一般說明

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Parteck^® M excipient achieves excellent compressibility while keeping the API stable throughout your manufacturing process and beyond. Based on directly compressible mannitol, it does not require further processing or high compression forces. The unique and large surface area of Parteck^® M excipient enables rapid disintegration and quick release regardless of the dosage. It is well suitable for tableting processesusing direct compression or granulation techniques such as wet granulation androller compaction. Parteck^® M is available in different particle sizes.
The specification of the product is part of the Emprove^® Material Qualification Dossier and can be found under "General Properties".

特點和優勢

• High compactibility at low compression forces
• Rapid disintegration and fast dissolution
• High dilution potential
• Non-hygroscopic, exceptionally low content of reducing sugars
• Uniform doses with homogenous distribution

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1