1.00383

DL-苹果酸

EMPROVE^® ESSENTIAL, Ph. Eur., NF, FCC, E 296

• 别名: DL-Malic acid, DL-Hydroxysuccinic acid, Hydroxybutanedioic acid
• 经验公式（希尔记法）: C₄H₆O₅
• CAS号: 6915-15-7
• 分子量: 134.09
• MDL號碼: MFCD00064212
• 分類程式碼代碼: 12352106
• 酶號碼: E296
• 酶委員會索引編號: 230-022-8

属性

• agency: NF; Ph. Eur.
• 品質等級: 500
• 法律遵循: FCC
• 產品線: EMPROVE^® ESSENTIAL
• 形狀: solid
• 自燃溫度: 349 °C
• 效力: >3200 mg/kg LD₅₀, oral (Rat)
• 技術: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH值: 2.3 (20 °C, 10 g/L in H₂O)
• mp: 128-132 °C
• 轉變溫度: flash point 203 °C
• 溶解度: 558 g/L
• 密度: 1.60 g/cm³ at 20 °C
• 應用: pharmaceutical; solid formulation
• 儲存溫度: 15-25°C
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
• InChI 密鑰: BJEPYKJPYRNKOW-UHFFFAOYSA-N

说明

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Malic acid is typically applied as acidulant and pH adjuster as well as taste modifier in pharmaceutical formulations and food. In addition, it has antioxidant properties.
DL-Malic acid Emprove^® Essential is mainly used in highly regulated pharmaceutical applications.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319
• 防範說明: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危險分類: Eye Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 397.4 °F
• 閃點（°C）: 203 °C