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主要文件

790304P

Avanti

Coag Reagent I

Avanti Research - A Croda Brand 790304P, powder

别名:

Coag Reagent, Coagulation Reagent I, contains DOPE:DOPS:DOPC (5:3:2 w/w)

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About This Item

UNSPSC代码:
12352211
NACRES:
NA.25
价格与库存信息目前不能提供

表单

powder

包装

pkg of 2 × 100 mg (790304P-200mg)
pkg of 1 × 25 mg (790304P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 790304P

应用

microbiology

脂质类型

phospholipids

运输

dry ice

储存温度

−20°C

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一般描述

Coag Reagent I comprises 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in the ratio 5:3:2 w/w. They are present predominantly in the synaptic vesicle membrane.[1] DOPC has choline group and DOPE comprises ethanolamine moiety. At neutral pH, DOPE and DOPC exist as a zwitterion whereas DOPS takes up a negative charge and has a serine group.[2]

应用

Coag Reagent I has been used in the preparation of small unilamellar vesicles (SUVs) for α-synuclein binding studies.[3][1] It may be used in the preparation of bilayers for reconstituting ryanodine receptor type 2 (RyR2) for single-channel recording studies.[4] It may be used for glass supported lipid bilayers preparation.[2]

生化/生理作用

Coag Reagent I mixed lipid is useful in the preparation of supported lipid bilayers and platelet membranes for coagulation studies.[2] It is used in the small unilamellar vesicles (SUVs) generation for α-synuclein and squalamine binding studies.[1]

包装

5 mL Clear Glass Sealed Ampule (790304P-200mg)
5 mL Clear Glass Sealed Ampule (790304P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2
Klipp RC, et al.
Heart Rhythm : the Official Journal of the Heart Rhythm Society, 15(4), 578-586 (2018)
A natural product inhibits the initiation of alpha-synuclein aggregation and suppresses its toxicity
Perni M, et al.
Proceedings of the National Academy of Sciences of the USA, 114(6), E1009-E1017 (2017)
Three-Dimensional Heterogeneous Structure Formation on a Supported Lipid Bilayer Disclosed by Single-Particle Tracking
Zhong Y & Wang G
Langmuir, 34(39), 11857-11865 (2018)
A M van den Besselaar et al.
Clinical chemistry, 43(7), 1215-1222 (1997-07-01)
To contribute to the development of a reference reagent for monitoring heparin therapy, a lyophilized partial thromboplastin time (PTT) reagent was prepared from synthetic dioleoylphosphatidylcholine, dioleoylphosphatidylserine, and dioleoylphosphatidylethanolamine, with colloidal silica as activator. The reagent, coded 91/558, was contained in
A M van den Besselaar et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 4(6), 895-903 (1993-12-01)
The activated partial thromboplastin time (aPTT) is the most popular test for monitoring of heparin therapy. The purpose of the present study was to show that an aPTT reagent with good response to heparin can be prepared from synthetic phosphoglycerides.

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