699851P

3A-MPLA

Avanti Research^™ - A Croda Brand 699851P, powder

• 别名: Monophosphoryl Tri-acyl Lipid A (Synthetic)
• 经验公式（希尔记法）: C₅₄H₁₀₆N₃O₁₇P
• CAS号: 1699735-80-2
• 分子量: 1100.40
• UNSPSC代码: 12352211
• NACRES: NA.25

属性

• 方案: >99% (HPLC)
• 表单: powder
• 包装: pkg of 1 × 1 mg (699851P-1mg); pkg of 1 × 5 mg (699851P-5mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand 699851P
• 应用: vaccine development
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2O.[NH4+]
• InChI: 1S/C54H103N2O17P.H3N/c1-4-7-10-13-16-19-20-23-26-29-32-35-46(61)70-41(34-31-28-25-22-18-15-12-9-6-3)37-45(60)56-48-51(64)52(73-74(66,67)68)42(38-57)72-54(48)69-39-43-49(62)50(63)47(53(65)71-43)55-44(59)36-40(58)33-30-27-24-21-17-14-11-8-5-2;/h40-43,47-54,
• InChI key: WBMOMCHVNLUEBA-MWYCKLIASA-N

说明

一般描述

Monophosphoryl lipid A (MPLA) is an analog of the lipid A moiety.[1] It is regarded as a detoxified derivative of the lipopolysaccharide (LPS).[2]

生化/生理作用

Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications.[3] It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.

包装

2 mL Amber Glass Crimp Cap Vial (699851P-1mg)

2 mL Amber Glass Crimp Cap Vial (699851P-5mg)

其他说明

For R&D use only. Not for drug, household, or other uses.

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): No data available
• 闪点(°C): No data available