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Merck

55452

Sigma-Aldrich

D-α-羟基异戊酸

≥98.0% (T)

别名:

(R)-2-羟基-3-甲基丁酸

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$349.00
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1 G
$349.00
5 G
$1,320.00

About This Item

经验公式(希尔记法):
C5H10O3
CAS号:
分子量:
118.13
Beilstein:
1721139
MDL號碼:
分類程式碼代碼:
51113400
PubChem物質ID:
NACRES:
NA.22

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化驗

≥98.0% (T)

形狀

solid

光學活性

[α]20/D −17±1°, c = 1% in chloroform

mp

64-67 °C

官能基

carboxylic acid
hydroxyl

SMILES 字串

CC(C)[C@@H](O)C(O)=O

InChI

1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t4-/m1/s1

InChI 密鑰

NGEWQZIDQIYUNV-SCSAIBSYSA-N

應用

D-α-Hydroxyisovaleric acid may be used in the preparation of biodegradable, optically active and isotactic poly(D-2-hydroxy-3-methylbutanoic acid).[1]

其他說明

该手性 α-羟基酸用于合成肽和缩酚酸肽。[2] 还可用作手性结构单元。[3] 通过二氧戊环酮中间体合成 α-取代 α-羟基酸。[4][5]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H.-O. Kim et al.
The Journal of Organic Chemistry, 52, 4531-4531 (1987)
R L Johnson
Journal of medicinal chemistry, 23(6), 666-669 (1980-06-01)
The following N-(alpha-hydroxylakanoyl) derivatives of Leu-Val-Phe-OCH3 were synthesized and tested for their ability to inhibit human amniotic renin: D- and L-alpha-hydroxyisocaproyl-Leu-Val-Phe-OCH3, D- and L-alpha-hydroxyisovaleryl-Leu-Val-Phe-OCH3, L-2-hydroxy-3-phenylpropanoyl-Leu-Val-Phe-OCH3, and D- and L-alpha-hydroxyphenylacetyl-Leu-Val-Phe-OCH3. Analysis of the compounds through the use of Dixion plots showed
W. Hartwig et al.
Liebigs Ann. Chem., 1952-1952 (1982)
Hetero-stereocomplex formation between substituted poly (lactic acid) s with linear and branched side chains, poly (l-2-hydroxybutanoic acid) and poly (d-2-hydroxy-3-methylbutanoic acid).
Tsuji H and Hayakawa T.
Polymer, 55(3), 721-726 (2014)
A Haese et al.
Journal of molecular biology, 243(1), 116-122 (1994-10-14)
Enniatin synthetase catalyzes the biosynthesis of N-methylated cyclohexadepsipeptides. The 347 kDa enzyme is encoded by the esyn1 gene of Fusarium scirpi and contains two domains (EA and EB) homologous to each other and to regions of other microbial peptide synthetases.

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