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Merck

U6628

Sigma-Aldrich

乌发醇

≥95%

别名:

Urs-12-ene-3,28-diol

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About This Item

经验公式(希尔记法):
C30H50O2
CAS号:
分子量:
442.72
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.25

化驗

≥95%

mp

223-225 °C (lit.)

應用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES 字串

C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C

InChI

1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1

InChI 密鑰

XUARCIYIVXVTAE-ZAPOICBTSA-N

基因資訊

mouse ... Nos2(18126)

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一般說明

Uvaolis是一种五环三萜化合物,通常从植物叶子中提取,例如罗布麻 (Apocynum venetum L.)、橄榄叶 (Olea europaea L.) 和牛至 (Origanum vulgare L.)。

應用

熊果醇已被用作视黄酸受体相关孤儿受体γ t (RORγt) 抑制剂,以研究强心苷还原酶2 (Cgr2) 对其代谢的作用。

生化/生理作用

熊果醇具有抗氧化、抗癌、抗炎和伤口愈合等药理特性。它还具有血管扩张、保肝和抗菌作用。熊果醇对一氧化氮 (NO) 释放具有抑制作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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X Z Xu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 25(4), 225-226 (2003-01-07)
To study the chemical components of Gentiana tizuensis distributed in Qinghai Province. Chromatography and spectral analyses were used to isolate the constituents and elucidate their structure. Four compounds were isolated and identified as uvaol, L-(+)-l-O-methyl-myo-inositol, ursolic acid,beta-sitosterol. All these components
L I Somova et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 11(2-3), 121-129 (2004-04-09)
The cardiotonic and antidysrhythmic effects of four triterpenoid derivatives, namely oleanolic acid (OA), ursolic acid (UA), and uvaol (UV), isolated from the leaves of African wild olive (Olea europaea, subsp. africana) as well as methyl maslinate (MM) isolated from the
De-Hong Huang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(3), 375-378 (2011-08-10)
To study the chemical constituents of Coleus forskohlii. Isolation and purification were carried out by silica gel column chromatographic and Toyopearl HW-40F. Compounds were identified and elucidated by spectral and chemical methods. Seven compounds were obtained from ethyl acetate extract
A Martins et al.
Anticancer research, 30(3), 829-835 (2010-04-16)
A bioassay-guided separation protocol, including the testing of the extracts, fractions and pure compounds for their ability to inhibit P-glycoprotein (the efflux pump responsible for the multidrug resistance of the used cell line) of mouse lymphoma cells containing the human
Margaret Alexander et al.
Cell host & microbe, 30(1), 17-30 (2021-11-26)
Bacterial activation of T helper 17 (Th17) cells exacerbates mouse models of autoimmunity, but how human-associated bacteria impact Th17-driven disease remains elusive. We show that human gut Actinobacterium Eggerthella lenta induces intestinal Th17 activation by lifting inhibition of the Th17

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