跳转至内容
Merck

537349

Sigma-Aldrich

乙酰乙酸乙酯

ReagentPlus®, 99%

别名:

EAA, 乙酰乙酸乙酯, 乙酰醋酸乙酯

登录查看公司和协议定价

选择尺寸

1 KG
$116.00
3 KG
$329.00

$116.00


预计发货时间2025年4月21日详情


获取大包装报价

选择尺寸

变更视图
1 KG
$116.00
3 KG
$329.00

About This Item

线性分子式:
CH3COCH2COOC2H5
CAS号:
分子量:
130.14
Beilstein:
385838
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$116.00


预计发货时间2025年4月21日详情


获取大包装报价

蒸汽密度

4.48 (vs air)

蒸汽压

1 mmHg ( 28.5 °C)

产品线

ReagentPlus®

方案

99%

自燃温度

580 °F

expl. lim.

9.5 %

沸点

181 °C (lit.)

mp

−43 °C (lit.)

溶解性

water: soluble 130 g/L at 20 °C

密度

1.029 g/mL at 20 °C (lit.)

官能团

ester
ketone

SMILES字符串

CCOC(=O)CC(C)=O

InChI

1S/C6H10O3/c1-3-9-6(8)4-5(2)7/h3-4H2,1-2H3

InChI key

XYIBRDXRRQCHLP-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

应用

乙酰乙酸乙酯是一种多功能试剂,可用作烷基化、共轭加成和缩合反应的亲核试剂。[1]其中一些应用有:
  • 在乙酰乙酸乙酯的α-碳上进行烷基化,然后水解和脱羧,即可产生各种甲基酮。[2]
  • 在MgCl2 和吡啶存在时,它还能在α-碳上进行酰化,得到合成重要的中间体。[3]
  • 它可以用于与脂族、芳族和杂芳族醛发生Knoevenagel缩合反应,生成α-亚烷基乙酰乙酸酯。[1][4]

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

164.3 °F - closed cup

闪点(°C)

73.5 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Knoevenagel-kondensationen mit titantetrachlorid/base?II: Alkyliden-und arylidenacet-bzw.-nitroessigester bei 0?22?.
Lehnert W
Tetrahedron, 28(3), 663-666 (1972)
Synthetic Applications of Dealkoxycarbonylations of Malonate Esters, β-Keto Esters, α-Cyano Esters and Related Compounds in Dipolar Aprotic Media-Part II.
Krapcho A P
Synthesis, 1982(11), 893-914 (1982)
Ethyl Acetoacetate.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Procedures for the acylation of diethyl malonate and ethyl acetoacetate with acid chlorides using tertiary amine bases and magnesium chloride.
Rathke MW and Cowan PJ.
The Journal of Organic Chemistry, 50(15), 2622-2624 (1985)
Genomes as resources for biocatalysis.
Jon D Stewart
Advances in applied microbiology, 59, 31-52 (2006-07-11)

商品

The Biginelli Reaction is an acid-catalyzed, three-component reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.

相关内容

The Biginelli Reaction is an acid catalyzed, threecomponent reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持