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M1381

Sigma-Aldrich

4-甲基伞形酮

≥98%

别名:

β-甲基伞形酮, 4-MU, 7-羟基-4-甲基香豆素

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25 G
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About This Item

经验公式（希尔记法）:
C10H8O3
CAS号:
90-33-5
分子量:
176.17
Beilstein:
142217
EC號碼:
201-986-7
MDL號碼:
MFCD00006866
分類程式碼代碼:
12352100
PubChem物質ID:
57654353
NACRES:
NA.22

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品質等級

200

化驗

≥98%

顏色

off-white to yellow

螢光

λex 372 nm; λem 445 nm in ethanol

SMILES 字串

CC1=CC(=O)Oc2cc(O)ccc12

InChI

1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3

InChI 密鑰

HSHNITRMYYLLCV-UHFFFAOYSA-N

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應用

4-羟甲香豆素主要用于合成药用化合物，并作为荧光探针的构建体。其应用包括用于合成：
  • 作为潜在的抗菌药物的香豆素三唑衍生物。[1]
  • 基于香豆素的荧光传感器，用于Mg2+ 检测。[2]
  • 吡喃香豆素衍生物，作为抗高血糖和抗血脂异常的药物。[3]
  • 香豆素哌嗪衍生物，作为潜在的多受体非典型抗精神病药物。[4]
  • 以4-羟甲香豆素T-抗原为底物制备endo-α-N-乙酰半乳糖氨基酶。 [5]

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF5029V
WXBF2575V
BCCK2017
WXBD6958V
BCCG6844

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Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents.
Shi Y and Zhou C-H
Bioorganic & Medicinal Chemistry Letters, 21(3), 956-960 (2011)
Tz-Ching Yeh et al.
Freshwater biology, 65(11), 1973-1988 (2020-12-09)
Bamboo, as a pioneer vegetation, often forms forests on bare lands after catastrophic landslides. Compared to evergreen forest soil, bamboo forest soil is much more labile, with a higher percentage of microbially derived organic carbon (OC), lower molecular weight, and
Na+ triggered fluorescence sensors for Mg2+ detection based on a coumarin salen moiety.
Dong Y, et al.
Organic Letters, 13(9), 2252-2255 (2011)
Yutaka Yoshioka et al.
Arthritis and rheumatism, 65(5), 1160-1170 (2013-01-22)
To clarify the roles of hyaluronan (HA) in joint inflammation and the process of joint destruction, using 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis, in a mouse model of collagen-induced arthritis (CIA) and in a monolayer culture of fibroblast-like synoviocytes
Di-tert-butylsilylene-directed α-selective synthesis of 4-methylumbelliferyl T-antigen.
Imamura A, et al.
Organic Letters, 7(20), 4415-4418 (2005)
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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