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Merck

493805

Sigma-Aldrich

5-(乙硫基)-1H-四唑

95%

别名:

5-乙基磺酰基-2H-四唑, 5-(乙基硫代)-2H-四唑

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2 G
$145.00

$145.00


国内现货,预计发货时间2025年4月21日详情


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2 G
$145.00

About This Item

经验公式(希尔记法):
C3H6N4S
CAS号:
分子量:
130.17
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$145.00


国内现货,预计发货时间2025年4月21日详情


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质量水平

方案

95%

mp

84-90 °C (lit.)

官能团

thioether

储存温度

2-8°C

SMILES字符串

CCSc1nnn[nH]1

InChI

1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)

InChI key

GONFBOIJNUKKST-UHFFFAOYSA-N

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一般描述

5-(乙硫基)-1H-四唑(ETT)是一种有效的活化剂,在寡核苷酸合成过程中,其激活核苷磷酰胺与核苷缩合形成二核苷磷酸盐。[1][2][3]

应用

  • 对称二核苷磷酸二酯的固相合成:探讨了5-乙硫基-1H-四氮唑在二核苷磷酸二酯的固相合成中的效率,强调了其在生物相关分子生产中的重要性(Ahmadibeni et al., 2007)。
  • RNA和核糖酶的合成、脱保护、分析和纯化:采用5-乙硫基-1H-四氮唑合成和加工RNA和核糖酶,重点介绍了其在分子生物学和基因工程研究中的关键作用(Wincott et al., 1995)。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

补充剂危害

储存分类代码

4.1A - Other explosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Benzimidazolium Triflate as an Efficient Promoter for Nucleotide Synthesis via the Phosphoramidite Method.
Yoshihiro Hayakawa et al.
The Journal of organic chemistry, 61(23), 7996-7997 (1996-11-15)
An efficient method for the isolation and purification of oligoribonucleotides.
Sproat B, et al.
Nucleosides, nucleotides & nucleic acids, 14(1-2), 255-273 (1995)
Gregor S Cremosnik et al.
Angewandte Chemie (International ed. in English), 53(1), 286-289 (2013-11-14)
P-Amidites can be used in iterative couplings to selectively give mixed P(III) -P(V) anhydrides. These intermediates can be oxidized followed by a rapid removal of the two terminal fluorenylmethyl groups. An iterative synthesis (coupling, oxidation, deprotection) of nucleoside oligophosphates can

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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