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Merck

331376

Sigma-Aldrich

苯基溴化镁 溶液

Phenylmagnesium bromide solution
1 of 1 reviewers received a sample product or took part in a promotion

1.0 M in THF

别名:

PhMgBr溶液

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50 ML
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50 ML
$73.40
4 X 25 ML
$79.00
100 ML
$83.10
800 ML
$258.00

About This Item

线性分子式:
C6H5MgBr
CAS号:
分子量:
181.31
Beilstein:
3588849
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22

$73.40


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质量水平

反应适用性

reaction type: Grignard Reaction

浓度

1.0 M in THF

密度

1.004 g/mL at 25 °C

SMILES字符串

Br[Mg]c1ccccc1

InChI

1S/C6H5.BrH.Mg/c1-2-4-6-5-3-1;;/h1-5H;1H;/q;;+1/p-1

InChI key

ANRQGKOBLBYXFM-UHFFFAOYSA-M

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应用

苯基溴化镁(PhMgBr)溶液是一种主要用于格氏反应的有机镁试剂,该反应可作为合成(S)-2-(二苯基甲基)吡咯烷(一种用于NMR分析的手性溶剂化试剂)中的关键步骤。[1]PhMgBr还可以与烷基氯化物进行钯催化的Grignard偶联,以良好的收率形成交叉偶联产物。[2]

其他说明

低于25°C条件下储存可能会导致结晶的形成。缓慢加热以重新溶解固体。

警示用语:

Danger

危险分类

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

1.4 °F - closed cup

闪点(°C)

-17 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Palladium?Catalyzed Coupling of Alkyl Chlorides and Grignard Reagents.
Frisch A C, et al.
Angewandte Chemie (International Edition in English), 41(21), 4056-4059 (2002)
A short synthesis of (S)-2-(diphenylmethyl) pyrrolidine, a chiral solvating agent for NMR analysis.
Bailey D J, et al.
Tetrahedron Asymmetry, 8(1), 149-153 (1997)
Ying Li et al.
Analytica chimica acta, 884, 106-113 (2015-06-16)
A novel molecularly imprinted electrochemical sensor based on Fe3O4 nanobeads immobilized on graphene (Fe3O4-MIP@RGO) has been developed for detecting 17β-estradiol (17β-E2) in water using reversible addition fragmentation chain transfer (RAFT) polymerization technique. 17β-E2 can be detected by this electrochemical sensor

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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