287644

(1R,2R)-(-)-伪麻黄碱

98%

• 别名: α-(1-甲氨基乙基)苄醇, (-)-ψ-麻黄碱, (-)-伪麻黄碱, (1R,2R)-(-)-2-(甲氨基)-1-苯丙醇, l-伪麻黄碱
• 线性分子式: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS号: 321-97-1
• 分子量: 165.23
• Beilstein: 2803417
• EC 号: 206-292-8
• MDL编号: MFCD00002203
• UNSPSC代码: 12352116
• PubChem化学物质编号: 24857283
• NACRES: NA.22

属性

• 方案: 98%
• 表单: solid
• 旋光性: [α]20/D −51°, c = 0.6 in ethanol
• mp: 118-120 °C (lit.)
• 官能团: amine; hydroxyl; phenyl
• SMILES字符串: CN[C@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m1/s1
• InChI key: KWGRBVOPPLSCSI-SCZZXKLOSA-N

说明

一般描述

(1R,2R)-(-)-Pseudoephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.[1]

应用

(1R,2R)-(-)-Pseudoephedrine may be used in the preparation of chiral relay ligands, which can catalyze the addition of diethylzinc to aldehydes leading to the corresponding secondary alcohol.[2] The immobilization of pseudoephedrine on Merrifield resin forms a chiral linker, which may be used for the asymmetric alkylation of amides via solid-phase approach.[3]

安全信息

• 象形图: GHS05,GHS07
• 警示用语：: Danger
• 危险声明: H302,H314,H317,H336
• 预防措施声明: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危险分类: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• 靶器官: Central nervous system
• 储存分类代码: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves