134910

(1R,2S)-(-)-麻黄碱

98%

• 别名: (-)-麻黄碱, (1R,2S)-(-)-α-(1-甲基氨基乙基)苄醇, (1R,2S)-(-)-2-甲氨基-1-苯丙醇, L-盐酸麻黄碱
• 线性分子式: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS号: 299-42-3
• 分子量: 165.23
• Beilstein: 2208730
• EC號碼: 206-080-5
• MDL號碼: MFCD00064257
• 分類程式碼代碼: 12352116
• PubChem物質ID: 24848190
• NACRES: NA.22

属性

• 品質等級: 200
• 化驗: 98%
• 形狀: solid
• 光學活性: [α]21/D −41°, c = 5 in 1 M HCl
• bp: 255 °C (lit.)
• mp: 37-39 °C (lit.)
• 密度: 1.124 g/mL at 25 °C (lit.)
• 官能基: amine; hydroxyl; phenyl
• 儲存溫度: 2-8°C
• SMILES 字串: CN[C@@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1
• InChI 密鑰: KWGRBVOPPLSCSI-WPRPVWTQSA-N

说明

一般說明

(1R,2S)-(-)-Ephedrine, a chiral β-amino alcohol, is commonly used as a chiral auxiliary in asymmetric synthesis.[1] It undergoes reduction to form (+)-methamphetamine.[2]

應用

通用手性合成子，[3]用于催化[4]以及制备光学纯亚砜[5]和噁唑烷。[6]

(1R,2S)-(-)-Ephedrine can be used in the preparation of optically active phosphine-phosphonite ligands[7] and chirally-substituted cyclopentadienyl (Cp) ligands.[8] It reacts with phosphorus trichloride to form (2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine.[9] It can also act as a chiral resolving agent for (±)-mandelic acid.[10]

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H314,H317
• 防範說明: P260 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 186.8 °F - closed cup
• 閃點（°C）: 86 °C - closed cup
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves