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Merck

178330

Sigma-Aldrich

4-氨基-1-丁醇

98%

别名:

4-羟基丁胺

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About This Item

线性分子式:
H2N(CH2)4OH
CAS号:
分子量:
89.14
Beilstein:
1731411
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

liquid

折射率

n20/D ~1.462 (lit.)

bp

206 °C (lit.)

mp

16-18 °C (lit.)

密度

0.967 g/mL at 25 °C (lit.)

SMILES 字串

NCCCCO

InChI

1S/C4H11NO/c5-3-1-2-4-6/h6H,1-5H2

InChI 密鑰

BLFRQYKZFKYQLO-UHFFFAOYSA-N

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應用

4-氨基-1-丁醇用于合成环胺
4-氨基-1-丁醇:
  • 在高度支化聚(β-氨基酯)(HPAEs) 进行基因传递。
  • 作为调节共聚物抗菌和溶血活性的侧链。
  • 在 (+)-福西汀、(+)-福西丁 和(-)-番茄红素 A的全合成中。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

219.2 °F - closed cup

閃點(°C)

104 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Highly branched poly (β-amino esters): Synthesis and application in gene delivery.
Cutlar L, et al.
Biomacromolecules, 16(9), 2609-2617 (2015)
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Scientific reports, 3, 3155-3155 (2013-11-07)
As the designs of polymer systems used to deliver nucleic acids continue to evolve, it is becoming increasingly apparent that the basic bulk manufacturing techniques of the past will be insufficient to produce polymer-nucleic acid nanocomplexes that possess the uniformity
Pieter Vader et al.
Pharmaceutical research, 29(2), 352-361 (2011-08-13)
Use of RNA interference as novel therapeutic strategy is hampered by inefficient delivery of its mediator, siRNA, to target cells. Cationic polymers have been thoroughly investigated for this purpose but often display unfavorable characteristics for systemic administration, such as interactions
Total Syntheses of Lycopodium Alkaloids (+)?Fawcettimine,(+)?Fawcettidine, and (−)?8?Deoxyserratinine.
Li H, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 124(2), 506-510 (2012)
Synthesis of cyclic amines and their alkyl derivatives from amino alcohols over supported copper catalysts.
Applied Catalysis, 53(1), 107-115 (1989)

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