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product name
4-(氨甲基)苯甲酸, 97%
化驗
97%
形狀
powder
反應適用性
reaction type: solution phase peptide synthesis
mp
≥300 °C (lit.)
應用
peptide synthesis
SMILES 字串
NCc1ccc(cc1)C(O)=O
InChI
1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)
InChI 密鑰
QCTBMLYLENLHLA-UHFFFAOYSA-N
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應用
4-(氨基甲基)苯甲酸(PAMBA)可用于合成:
- 钴羧酸膦酸酯。
- Apoptozole(Az),具有促进突变囊性纤维化跨膜传导调节因子(CFTR)氯通道活性的膜运输的细胞效力。
- 环肽,由 L-谷氨酸和 3-氨基苯甲酸组成,可用作各种阳离子和阴离子的受体。
- 生物活性肽,具有有效的 GPR54(G 蛋白偶联受体)激动活性。
其他說明
4-(氨基甲基)苯甲酸也是一种抗出血剂,用于治疗内出血。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Molecular nutrition & food research, 56(5), 753-760 (2012-06-01)
Dietary peptides are potent stimulators of cholecystokinin (CCK) secretion, but the sensing mechanism in CCK-producing cells is poorly understood. Recently, it has been demonstrated that the calcium-sensing receptor (CaSR) mediates CCK secretion induced by amino acids. We investigated the role
Fmoc?based solid?phase synthesis of GPR54?agonistic pentapeptide derivatives containing alkene?and fluoroalkene?dipeptide isosteres.
Pept. Sci., 88(2), 272-278 (2007)
Journal of the American Society for Mass Spectrometry, 23(3), 475-482 (2012-01-06)
While recent studies have shown that for some peptides, such as oligoglycines and Leu-enkephalin, mid-sized b fragment ions exist as a mixture of oxazolone and macrocycle structures, other primary structure motifs, such as QWFGLM, are shown to exclusively give rise
Large increase in cation binding affinity of artificial cyclopeptide receptors by an allosteric effect.
Journal of the American Chemical Society, 121(25), 5846-5855 (1999)
Synthesis of model glycolipids having two long alkyl chains.
Carbohydrate research, 277(2), C1-C3 (1995-11-22)
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