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质量水平
方案
≥99%
表单
liquid
折射率
n20/D 1.561 (lit.)
沸点
273 °C (lit.)
mp
9-12 °C (lit.)
溶解性
alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
water: insoluble(lit.)
密度
1.254 g/mL at 25 °C (lit.)
官能团
nitro
SMILES字符串
COc1ccccc1[N+]([O-])=O
InChI
1S/C7H7NO3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5H,1H3
InChI key
CFBYEGUGFPZCNF-UHFFFAOYSA-N
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一般描述
应用
2-Nitroanisole has been employed as solvatochromic probe to examine cybotactic region of pure and mixed supercritical fluid solvent systems[3].
警示用语:
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
M J Miller et al.
Drug metabolism and disposition: the biological fate of chemicals, 13(5), 527-531 (1985-09-01)
The pharmacokinetics and metabolism of o-nitroanisole (ONA) were studied in male Fischer 344 rats. Three dose levels of [14C]ONA (5.0, 50, or 500 mg/kg) were administered orally to rats and daily excreta were analyzed for 14C. Since the highest dose
Y Miura et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 100(2), 249-252 (1991-01-01)
1. The cytochrome P-450 content (0.75 +/- 0.13 nmol/mg microsomal protein) in musk shrew (suncus, Suncus murinus) liver microsomes was lower than that (1.30 +/- 0.26) in rat liver microsomes, but it is approximately the same level as in the
Marie Stiborová et al.
Interdisciplinary toxicology, 2(1), 24-27 (2009-03-01)
An aromatic amine, o-anisidine (2-methoxyaniline) and its oxidative counterpart, 2-nitroanisole (2-methoxynitrobenzene), are the industrial and environmental pollutants causing tumors of the urinary bladder in rats and mice. Both carcinogens are activated to the same proximate carcinogenic metabolite, N-(2-methoxyphenyl)hydroxylamine, which spontaneously
Markéta Miksanová et al.
Chemical research in toxicology, 17(5), 663-671 (2004-05-18)
2-Nitroanisole (2-NA) is an important industrial pollutant and a potent carcinogen for rodents. Determining the capability of humans to metabolize 2-NA and understanding which human cytochrome P450 (P450) enzymes are involved in its activation and/or detoxification are important to assess
J G Hengstler et al.
Scandinavian journal of work, environment & health, 21(1), 36-42 (1995-02-01)
The aim of the study was to detect single-strand breaks in deoxyribonucleic acid (DNA) in mononuclear blood cells of fire fighters exposed to o-nitroanisole and other substances released into the environment during an accident in a chemical plant. The level
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