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142360

Sigma-Aldrich

4-苄基哌啶

99%

别名:

苯基(4-哌啶基)甲烷

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About This Item

经验公式（希尔记法）:
C12H17N
CAS号:
31252-42-3
分子量:
175.27
Beilstein:
132339
EC 号:
250-535-0
MDL编号:
MFCD00006006
UNSPSC代码:
12352100
PubChem化学物质编号:
24848521
NACRES:
NA.22
价格与库存信息目前不能提供

方案

99%

折射率

n20/D 1.537 (lit.)

沸点

279 °C (lit.)

mp

6-7 °C (lit.)

密度

0.997 g/mL at 25 °C (lit.)

官能团

phenyl

SMILES字符串

C1CC(CCN1)Cc2ccccc2

InChI

1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2

InChI key

ABGXADJDTPFFSZ-UHFFFAOYSA-N

基因信息

rat ... Htr2a(29595) , Htr2c(25187)

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相关类别

一般描述

4-苄基哌啶是多巴胺选择性释放剂[1]。它是治疗可卡因成瘾的潜在候选药物[1]。

应用

4-苄基哌啶被用于研究雄性B6C3F1小鼠和Sprague-Dawley大鼠的灌注肝脏中1,3-丁二烯及其氧化代谢产物的代谢[2]。
用于合成以下物质的反应物：
  • 抗增殖剂
  • GABA吸收抑制剂
  • 吡啶类
  • 组胺 H3 拮抗剂
  • 具有胆碱能和神经保护作用的多功能药物，可用于治疗阿尔茨海默氏症和神经血管疾病
  • 通过亲核取代，发挥抗血清素、抗血小板、血液流变学、抗心律失常和抗氧化作用

生化/生理作用

4-苄基哌啶能够抑制大鼠脑单胺氧化酶-A和-B的活性[3]。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

233.6 °F - closed cup

闪点(°C)

112 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
12903TH
S43132
14111HH
08921CH
05316CH

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