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Merck

M73206

Sigma-Aldrich

4-甲基哌啶

96%

别名:

γ-甲基哌啶, 4-哌可啉

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5 ML
$51.60
100 ML
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500 ML
$222.00

About This Item

经验公式(希尔记法):
C6H13N
CAS号:
分子量:
99.17
Beilstein:
1083
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$51.60


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质量水平

方案

96%

表单

liquid

折射率

n20/D 1.446 (lit.)

沸点

124 °C (lit.)

密度

0.838 g/mL at 25 °C (lit.)

SMILES字符串

CC1CCNCC1

InChI

1S/C6H13N/c1-6-2-4-7-5-3-6/h6-7H,2-5H2,1H3

InChI key

UZOFELREXGAFOI-UHFFFAOYSA-N

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应用

4-甲基哌啶可用于合成以下生物活性化合物:
  • 二甲基双(4-甲基哌啶-二硫代氨基甲酸-S,S′)-锡(IV)[1]
  • E)-4-(4′-甲基哌啶子基-N-烷氧基)二苯乙烯[2]
  • E)-查耳酮的 4-甲基哌啶子基烷硫基和 4-甲基哌啶子基烷氧基衍生物[3]

它还可以作为脱保护试剂,用于在固相肽合成期间从氨基酸中除去 Fmoc 基团。[4]

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

55.4 °F - closed cup

闪点(°C)

13 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preparation, Spectroscopy, Antimicrobial Assay, and X-Ray Structure of Dimethyl bis-(4-methylpiperidine dithiocarbamato-S, S)-tin (IV).
REHMAN Z, et al.
Turkish Journal of Chemistry, 31(4), 435-442 (2007)
Synthesis and antimicrobial activity of new (E)-4-[piperidino (4'-methylpiperidino-, morpholino-) N-alkoxy] stilbenes.
Wyrzykiewicz E, et al.
European Journal of Medicinal Chemistry, 41(4), 519-525 (2006)
Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones.
Nowakowska Z, et al.
European Journal of Medicinal Chemistry, 43(4), 707-713 (2008)
Efficient synthesis of peptides with 4-methylpiperidine as Fmoc removal reagent by solid phase synthesis.
Galeano V, et al.
Journal of the Mexican Chemical Society, 58(4), 386-392 (2014)
Aline de Souza et al.
Drug delivery and translational research, 10(6), 1771-1787 (2020-08-26)
Peptide-mediated targeting to colorectal cancer can increase selectivity and specificity of this cancer diagnosis acting as biomarkers. The present work aimed to select peptides using the phage display technique and associate the peptides with polymeric nanospheres in order to evaluate

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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