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Merck

ADORA3

adenosine A3 receptor

别名:
A3AR, AD026, bA552M11.5
物种:
UniProtKB ID:
基因ID:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

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Small Molecule - Agonist

货号
说明
物种
腺苷, ,
物种
human
间型霉素 A, from Streptomyces kaniharaensis, ≥98% (HPLC),
物种
human
腺苷, United States Pharmacopeia (USP) Reference Standard,
物种
human
腺苷, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
腺苷, phyproof® Reference Substance,
物种
human

Small Molecule - Antagonist

货号
说明
物种
VUF 5574, ,
物种
human
酪胶 盐酸盐, ≥98%,
物种
human
S)-(−)-Bay K8644, ≥98% (HPLC), solid,
物种
human, rat
3-Deazaadenosine, ,
物种
rat
咖啡因, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168), Chemicon®, from rabbit,
物种反应性
rat
应用
ELISA
immunocytochemistry

western blot
Monoclonal Anti-ADORA3 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

Small Molecule - Inhibitor

货号
说明
物种
EHNA 盐酸盐, ≥98% (HPLC),
物种
human
Dilazep dihydrochloride, powder,
物种
human
5′-脱氧-5′-腺苷, ,
物种
human, rat, mouse
α-萘黄酮, ≥98%,
物种
human, rat
高良姜黄素, autophagy inducing flavonoid,
物种
human, rat

Small Molecule - Ligand

货号
说明
物种
2-氯-2′-脱氧腺苷, antileukemic,
物种
rat, human
1,7-二甲基黄嘌呤, ~98%, solid,
物种
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
物种
human, rat
腺苷, ≥99%,
物种
human, rat
茶碱, anhydrous, ≥99%, powder,
物种
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
2-氟肾上腺素-9-β-D-阿拉伯呋喃糖苷, DNA synthesis and methylation inhibitor,
物种
rat, human
2-碘腺苷, 97%,
物种
human, rat
2-氟腺苷, 97%,
物种
rat, human
2-氯腺苷, ,
物种
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ADORA3,
物种
human
MISSION® esiRNA, targeting human TMIGD3,
物种
human