P9389
Poly(deoxyguanylic-deoxycytidylic) acid sodium salt
double stranded, alternating copolymer
Synonym(s):
Poly(dG-dC) • Poly(dG-dC)
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 units | Check Cart for Availability | $751.00 |
About This Item
Biological source:
synthetic (organic)
Form:
powder or solid
Storage temp.:
−20°C
General description
Poly(deoxyguanylic-deoxycytidylic) acid (poly(dG-dC)) undergoes salt dependent conformational transition. Under high-salt, it exists as a left-handed double helix and at low-salt it displays B-DNA conformation. However on immobilization, poly(dG-dC) takes up A DNA form.
Application
Poly(deoxyguanylic-deoxycytidylic) acid sodium salt has been used:
- in electrophoretic mobility shift assay of transcription factor IIIB complex
- as synthetic copolymers for circular dichroism (CD) spectroscopy studies[1]
- as a positive control in liquid scintillation counting
Poly(deoxyguanylic-deoxycytidylic) acid (Poly(dG-dC) • Poly(dG-dC)) is an alternating copolymer, self-complementary, double-stranded DNA model for conformational studies of DNA structure dynamics and drug interaction.
Other Notes
Alternating copolymer; self-complementary, form double-stranded complex
One unit will yield an A260 of 1.0 in 1.0 ml 20 mM sodium phosphate/100 mM NaCl, pH 7.0 (1cm light path).
1 of 1
This Item | |||
|---|---|---|---|
| biological source synthetic (organic) | biological source - | biological source - | biological source synthetic (organic) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| form powder or solid | form powder | form liquid | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P9389-25UN | 04061833493199 |
| P9389-10UN | 04061834402954 |