N142

NO-711 hydrochloride

≥98% (HPLC), GABA uptake inhibitor, powder

• Synonym(s): 1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride, NNC-711 hydrochloride
• Empirical Formula (Hill Notation): C₂₁H₂₂N₂O₃ · HCl
• CAS Number: 145645-62-1
• Molecular Weight: 386.87
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278817
• NACRES: NA.77
• MDL number: MFCD00153853
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Properties

• Product Name: NO-711 hydrochloride, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• solubility: H₂O: 10 mg/mL at 60 °C
• SMILES string: Cl[H].OC(=O)C1=CCCN(CCO\N=C(/c2ccccc2)c3ccccc3)C1
• InChI: 1S/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18;/h1-6,8-12H,7,13-16H2,(H,24,25);1H
• InChI key: YZYRTEYMUTWJPL-UHFFFAOYSA-N
• Gene Information: human ... GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

Description

Application

NO-711 hydrochloride is suitable for use as γ-aminobutyric acid (GABA) transporter-1 (GAT-1) antagonists or GABA uptake inhibitor.

Biochem/physiol Actions

NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier.

NO-711 is a potent and selective GABA uptake inhibitor.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Disclaimer

Photosensitive

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)