T1698

Tetradecylthioacetic acid

≥97% (NMR)

• Synonim(y): TTA
• Wzór liniowy: C₁₄H₂₉-S-CH₂COOH
• Numer CAS: 2921-20-2
• Masa cząsteczkowa: 288.49
• NACRES: NA.77
• PubChem Substance ID: 24278726
• UNSPSC Code: 12352200
• MDL number: MFCD00128230
• Assay: ≥97% (NMR)
• Quality level: 100

Właściwości

• Quality Level: 100
• assay: ≥97% (NMR)
• color: white
• solubility: DMSO: soluble ≥22 mg/mL
• SMILES string: CCCCCCCCCCCCCCSCC(O)=O
• InChI: 1S/C16H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-15-16(17)18/h2-15H2,1H3,(H,17,18)
• InChI key: IPBCWPPBAWQYOO-UHFFFAOYSA-N
• Gene Information: human ... PPARA(5465)

Opis

Biochem/physiol Actions

PPARα agonist; activation in ranking order: PPARδ > PPARα > PPARγ

Tetradecylthioacetic acid (TTA) is known to modulate lipid homeostasis. TTA can increase fatty acid oxidation and ketogenesis, which can subsequently prevent adiposity and insulin resistance. Furthermore, TTA can enhance cardiac functions during experimental heart failure.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Packaged under nitrogen.

Preparation Note

Tetradecylthioacetic acid is soluble in DMSO at a concentration that is greater than or equal to 22 mg/ml.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)