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Merck

T0699

Trichloroacetic acid solution

6.1 N

Synonim(y):

TCA

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100 ML

653,00 zł

653,00 zł


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Informacje o tej pozycji

Wzór liniowy:
Cl3CCOOH
Numer CAS:
Masa cząsteczkowa:
163.39
UNSPSC Code:
12352106
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
970119
Concentration:
6.1 N, ~100 % (w/v)
Form:
liquid

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form

liquid

Quality Level

concentration

6.1 N, ~100 % (w/v)

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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Ta pozycja
T91599123091228
concentration

6.1 N, ~100 % (w/v)

concentration

-

concentration

-

concentration

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

-

form

flakes

form

crystals, flakes

General description

Trichloroacetic acid (TCA) is a strong acid. At the pH of drinking water, TCA exists almost in salt form.

Application

Trichloroacetic acid solution has been used:
  • in indoleamine 2,3-dioxygenase (IDO) enzyme assay to hydrolyze N-formylkynurenine and produce kynurenine
  • in the proliferation of human pulmonary artery smooth muscle cells (HPASMCs)
  • to treat ground tissue and precipitate proteins during protein extraction and quantification

Biochem/physiol Actions

Trichloroacetic acid solution is traditionally used to precipitate protein. It can be used to determine protein concentration by quantitative precipitation. Trichloroacetic acid can also be used as a decalcifier and fixative in microscopy.
Trichloroacetic acid (TCA) with no known systemic toxicity, is used as a time-honored agent for superficial peeling. It is a peroxisome proliferator.
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signalword

Danger

target_organs

Respiratory system

Klasa składowania

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1 - STOT SE 3


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Guillaume Laflamme et al.
Cell reports, 26(11), 2875-2889 (2019-03-14)
The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
Hikmat Al-Ahmadie et al.
Cancer discovery, 4(9), 1014-1021 (2014-06-18)
Metastatic solid tumors are almost invariably fatal. Patients with disseminated small-cell cancers have a particularly unfavorable prognosis, with most succumbing to their disease within two years. Here, we report on the genetic and functional analysis of an outlier curative response
Inga Müller et al.
PloS one, 9(5), e97285-e97285 (2014-05-27)
Members of the MYC family are the most frequently deregulated oncogenes in human cancer and are often correlated with aggressive disease and/or poorly differentiated tumors. Since patients with MYCN-amplified neuroblastoma have a poor prognosis, targeting MYCN using small molecule inhibitors
Valentina Folgiero et al.
Oncotarget, 5(8), 2052-2064 (2014-06-07)
Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an interferon (IFN)-γ-inducible enzyme that degrades tryptophan into kynurenine, which, in turn, inhibits effector T cells and promotes regulatory T-cell (Treg) differentiation. It

Protokoły

Aktywność proteinazy K mierzona za pomocą spektrofotometrii przy użyciu substratu hemoglobiny, kluczowa dla charakterystyki enzymu.

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

This procedure may be used for the determination of Amyloglucosidase activity using starch as the substrate.

This procedure may be used for all Ficin products.

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Numer pozycji handlu globalnego

SKUNUMER GTIN
T0699-100ML04061837335778

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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