SAB4700051

Monoclonal Anti-CD3-PE antibody produced in mouse

clone APA1/1, purified immunoglobulin, buffered aqueous solution

• Synonim(y): Anti-CD3 (activation epitope)
• Kod UNSPSC: 12352203
• NACRES: NA.44

Właściwości

• pochodzenie biologiczne: mouse
• białko sprzężone: phycoerythrin (R-PE) conjugate
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: APA1/1, monoclonal
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human, mouse
• stężenie: 0.1 mg/mL
• metody: flow cytometry: suitable
• izotyp: IgG1
• numer dostępu NCBI: NM_000733.3
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... CD3(916)

Opis

Opis ogólny

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Immunogen

Purified human CD3 proteins isolated from thymus

Zastosowanie

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Cechy i korzyści

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Postać fizyczna

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable