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Merck

P6280

Pyridoxine hydrochloride

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonim(y):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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Wybierz wielkość

10 G

214,00 zł

25 G

319,00 zł

100 G

1040,00 zł

214,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C8H11NO3 · HCl
Numer CAS:
58-56-0
Masa cząsteczkowa:
205.64
NACRES:
NA.21
PubChem Substance ID:
24898752
eCl@ss:
34058008
UNSPSC Code:
12161900
EC Number:
200-386-2
MDL number:
MFCD00012807
Beilstein/REAXYS Number:
3632435

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InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

product line

BioReagent

assay

≥98% (HPLC)

form

powder

mol wt

Mw 205.64 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

mp

214-215 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

application(s)

agriculture

Quality Level

200

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Ta pozycja
BP458P4100000P4722
Pyridoxine hydrochloride BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Sigma-Aldrich

P6280

Pyridoxine hydrochloride

Pyridoxine hydrochloride British Pharmacopoeia (BP) Reference Standard

BP458

Pyridoxine hydrochloride

Pyridoxine hydrochloride European Pharmacopoeia (EP) Reference Standard

P4100000

Pyridoxine hydrochloride

Pyridoxine hydrochloride meets USP testing specifications

Sigma-Aldrich

P4722

Pyridoxine hydrochloride

technique(s)

cell culture | insect: suitable, cell culture | plant: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

-

assay

≥98% (HPLC)

assay

-

assay

-

assay

98.0-102.0% dry basis

application(s)

agriculture

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

form

powder

form

solid

form

solid

form

powder

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

color

white to off-white

color

white

color

-

color

white

General description

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate. 

Application

Pyridoxine hydrochloride has been used:
  • as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
  • as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
  • as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem/physiol Actions

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.
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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
0000464783
0000464783
0000499249
0000499248
0000499249

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Wanliang Shi
Antibiotics (Basel, Switzerland), 10(8) (2021-08-28)
Susceptibility testing of tuberculosis (TB) drugs on Mycobacterium tuberculosis is essential for the rapid detection of strains resistant to the drugs, providing the patient with effective treatment, and preventing the spread of drug-resistant TB strains. Pyrazinamide (PZA) is one of
Carmela Vigorito et al.
International journal of molecular sciences, 20(9) (2019-05-11)
(1) The beneficial effects of hydrogen sulfide (H2S) on the cardiovascular and nervous system have recently been re-evaluated. It has been shown that lanthionine, a side product of H2S biosynthesis, previously used as a marker for H2S production, is dramatically
N Milne et al.
FEMS yeast research, 20(2) (2019-09-27)
We present a teaching protocol suitable for demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of industrially relevant yeasts Saccharomyces cerevisiae and Yarrowia lipolytica, using β-carotene production as a case study. The protocol details all steps required to
Imène Mensi et al.
Bio-protocol, 7(2), e2111-e2111 (2017-01-20)
Sugarcane (interspecific hybrids of Saccharum species) is an economically important crop that provides 70% of raw table sugar production worldwide and contributes, in some countries, to bioethanol and electricity production. Leaf scald, caused by the bacterial plant pathogen Xanthomonas albilineans
Ilan Matok et al.
Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
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Produkty

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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