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Kluczowe dokumenty
I9401
Interleukin-1β human
IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonim(y):
IL-1β, Lymphocyte activating factor
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About This Item
Numer MDL:
Kod UNSPSC:
12352202
Polecane produkty
pochodzenie biologiczne
human
Poziom jakości
rekombinowane
expressed in E. coli
Próba
≥98% (SDS-PAGE)
Postać
lyophilized powder
siła działania
≤12 pg/mL ED50
jakość
endotoxin tested
masa cząsteczkowa
17.3 kDa
opakowanie
pkg of 5 and 25 μg
pkg of 25 μg
metody
cell culture | mammalian: suitable
kolor
white to off-white
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
human ... IL1B(3553)
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Działania biochem./fizjol.
Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.
Postać fizyczna
Lyophilized from a 0.2 μm filtered buffered solution.
Komentarz do analizy
The biological activity is measured by the dose-dependent stimulation of MTS cleavage by murine D10S cells.
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Kod klasy składowania
13 - Non Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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