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A2056

Acetyl coenzyme A trisodium salt

≥93% (HPLC), powder

Synonim(y):

Acetyl-S- CoA, Acetyl CoA

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Do Państwa/SKUDostępnośćCena netto
1 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
350,00 zł
5 mg
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1020,00 zł
10 mg
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1330,00 zł
25 mg
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2050,00 zł
100 mg
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6360,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C23H35N7O17P3S · 3Na
Numer CAS:
Masa cząsteczkowa:
875.52
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Form:
powder
Assay:
≥93% (HPLC)
Solubility:
H2O: 100 mg/mL

350,00 zł


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Quality Segment

assay

≥93% (HPLC)

form

powder

solubility

H2O: 100 mg/mL

storage temp.

−20°C

SMILES string

O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[3Na]

InChI

1S/C23H38N7O17P3S.Na/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30;/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38);/q;+1/p-1/t13-,16-,17-,18?,22-;/m1./s1

InChI key

HNLIOWFIXSPFEC-WLYMNMRISA-M

Application

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl CoA is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Krebs cycle). Acetyl CoA is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. Acetyl CoA is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.
An essential cofactor in enzymatic acetyl transfer reactions.

Biochem/physiol Actions

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions.
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.

Preparation Note

Prepared enzymatically

Other Notes

For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.
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Ta pozycja
A2181C3019A6861
solubility

H2O: 100 mg/mL

solubility

H2O: soluble 100 mg/mL, clear, colorless

solubility

-

solubility

-

assay

≥93% (HPLC)

assay

≥93% (HPLC)

assay

≥93%

assay

-

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

form

powder

form

powder

form

powder

form

solution

Gene Information

human ... CHAT(1103), HAT1(8520), KAT2A(2648), KAT2B(8850), KAT5(10524)
mouse ... HAT1(107435), KAT2A(14534), KAT2B(18519), KAT5(81601)
rat ... HAT1(296501), KAT2A(303539), KAT2B(301164), KAT5(192218)

Gene Information

human ... CHAT(1103), HAT1(8520), KAT2A(2648), KAT2B(8850), KAT5(10524)
mouse ... HAT1(107435), KAT2A(14534), KAT2B(18519), KAT5(81601)
rat ... HAT1(296501), KAT2A(303539), KAT2B(301164), KAT5(192218)

Gene Information

-

Gene Information

human ... ACACB(32)


Klasa składowania

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)



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Questions

1–4 of 4 Questions  
  1. For Product No. A2056, Acetyl Coeznyme A, why is the formula weight listed on the website and the formula weight listed on the label different?

    1 answer
    1. The difference in the formula weights reported for Product No. A2056, Acetyl Coenzyme A, on the website versus the label is due to the sodium and water content of the product which may vary from lot to lot.  The formula weight of the free base is reported on the website, however on the label, variations in sodium and water content will reflect differences in formula weights reported on the label for a specific lot of product.

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  2. What is the formula weight for the Product No. A2056, Acetyl Coenzyme A?

    1 answer
    1. The formula weight for the Product No. A2056, Acetyl Coenzyme A, as reported on the website is for the free base with a weight of 809.57 daltons.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. What is the solution stability for the A2056, Acetyl Coenzyme A?

    1 answer
    1. The solution stability is reported as followed:  A solution of the product can be stored in neutral buffer or below (pH 3-7) for no longer than two weeks at -20°C when divided into aliquots. This is recommended for keeping the solution stable. It would be better to prepare fresh solutions and use soon after.

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