905H-0

Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002)

Mouse and Rabbit Monoclonal Antibody

• Synonim(y): Cytokeratin 5 (EP1601Y) + Cytokeratin 14 (LL002) Mouse and Rabbit Monoclonal Antibody
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse; rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: EP1601Y + LL002, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: bottle of 1.0 mL predilute (905H-07); bottle of 7.0 mL predilute (905H-08)
• producent / nazwa handlowa: Cell Marque^®
• stężenie: 0.1-1.5 μg/mL (predilute)
• izotyp: IgG3; IgG
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• informacje o genach: human ... KRT5(3852)

Opis

Opis ogólny

Cytokeratin 5 is an intermediate filament protein of 58 kD molecular wt. amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.[1] Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.[1] Anti-Cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma.[2] Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas immunostain with CK5. Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas[3] from other epithelial tumors.[4][5] Anti-CK5, along with anti-CK14, has found application in identifying the basaloid phenotype of breast carcinoma, a tumor with poor prognosis.[6][7][8]

Jakość

IVD

IVD

IVD

RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

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Inne uwagi

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Informacje prawne

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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