86614

Tetraethylammonium chloride

BioUltra, Molecular Biology, ≥99.0% (AT)

• Synonim(y): Etamon chloride, TEAC, TEA chloride
• Wzór liniowy: (C₂H₅)₄N(Cl)
• Numer CAS: 56-34-8
• Masa cząsteczkowa: 165.70
• UNSPSC Code: 12352107
• NACRES: NA.26
• PubChem Substance ID: 57653171
• EC Number: 200-267-5
• Beilstein/REAXYS Number: 3563247
• MDL number: MFCD00011828

Właściwości

• grade: Molecular Biology
• Quality Segment: 100
• product line: BioUltra
• assay: ≥99.0% (AT)
• form: powder
• mol wt: 165.70 g/mol
• technique(s): gas chromatography (GC): suitable
• impurities: DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: bromide (Br^-): ≤500 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.03, λ: 280 nm A_max: 0.03
• SMILES string: [Cl-].CC[N+](CC)(CC)CC
• InChI: 1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
• InChI key: YMBCJWGVCUEGHA-UHFFFAOYSA-M

Opis

General description

Tetraethylammonium (TEA), a simple quaternary ammonium compound, is commonly used to block potassium channels. It can physically enter the pore and block the channel. Additionally, TEA either imitates or antagonizes the actions of choline and acetylcholine, two other quaternary ammonium ions.

Application

Tetraethylammonium chloride has been used:

• as a pharmacological agent in electrophysiology to study its pharmacological effects on Cnidarians[1]
• as a component in refolding buffer for protein refolding[2]
• to puff onto isolated patches to block voltage-gated K⁺ (Kv3) channels and post-hoc evaluation[3]

Features and Benefits

• Assay: ≥99.0% (AT), BioUltra, for molecular biology
• Suitable for gas chromatography (GC)

Other Notes

TEACl method of DNA-DNA hybridization

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: 201.2 °F - closed cup
• flash_point_c: 94 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves