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62962

Sigma-Aldrich

L-α-Lysophosphatidylcholine

egg yolk, ≥99.0% (TLC)

Synonim(y):

3-sn-Lysophosphatidylcholine, L-α-Lysolecithin

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About This Item

Numer MDL:
MFCD00131444
Kod UNSPSC:
51321705
NACRES:
NA.25

pochodzenie biologiczne

egg yolk

opis

zwitterionic

Próba

≥99.0% (TLC)

Postać

powder or solid

skład

16:0, ~69% (fatty acid)
18:0, ~27% (fatty acid)
18:1, ~3% (fatty acid)

rozpuszczalność

chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow

grupa funkcyjna

phospholipid

typ lipidu

phosphoglycerides

Warunki transportu

wet ice

temp. przechowywania

−20°C

Powiązane kategorie

Zastosowanie


  • The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).

  • Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).

Działania biochem./fizjol.

3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .

Inne uwagi

Preparation of demembranated frog sperm chromatin

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Priscila M Hiraiwa et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 93(7), 727-736 (2018-08-18)
Trypanosomatid parasites are causative agents of neglected human diseases. Their lineage diverged early from the common eukaryotic ancestor, and they evolved singular mechanisms of gene expression that are crucial for their survival. Studies on unusual and essential molecular pathways lead
Fengfeng Lu et al.
Neuroscience bulletin, 35(3), 434-446 (2019-01-27)
The obstacle to successful remyelination in demyelinating diseases, such as multiple sclerosis, mainly lies in the inability of oligodendrocyte precursor cells (OPCs) to differentiate, since OPCs and oligodendrocyte-lineage cells that are unable to fully differentiate are found in the areas
Nuclear envelope assembly following mitosis.
R Pfaller et al.
Methods in enzymology, 219, 60-72 (1992-01-01)
Beibei Duan et al.
Molecules (Basel, Switzerland), 26(6) (2021-04-04)
Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group
Harvey T McMahon et al.
Nature, 438(7068), 590-596 (2005-12-02)
Membrane curvature is no longer seen as a passive consequence of cellular activity but an active means to create membrane domains and to organize centres for membrane trafficking. Curvature can be dynamically modulated by changes in lipid composition, the oligomerization
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