101R-1

CD1a (EP3622) Rabbit Monoclonal Primary Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: EP3622, monoclonal
• Application: IHC (p)
• Citations: 5

Właściwości

• biological source: rabbit
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP3622, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (101R-14), vial of 0.5 mL concentrate (101R-15), bottle of 1.0 mL predilute (101R-17), pkg of 1.0 mL concentrate (101R-16), bottle of 7.0 mL predilute (101R-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotype: IgG1
• control: skin, thymus
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: membranous
• Gene Information: human ... CD1A(909)

Opis

General description

CD1a is a non-polymorphic, major histocompatibility complex, class I-related cell surface glycoprotein (45 to 55 kDa), and is expressed in association with β-microglobulin.[1] In normal tissues, anti-CD1a reacts with cortical thymocytes, Langerhans cells, interdigitating cells, and rare antigen-presenting cells of the lymph node.[2] CD1a positivity has also been seen in Langerhans cell histiocytosis (histiocytosis X)[3], and a subset of pre-T lymphoblastic lymphoma/leukemia (cortical T LBL/L).[4]

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

CD1a Positive Control Slides, Product No. 101S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

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Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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