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MABN742

Sigma-Aldrich

Anti-Neuroligin-1, clone 1C9.1 Antibody

clone 1C9.1, from mouse

Synonim(y):

neuroligin 1, NLGN1, neuroligin-1

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

mouse

Poziom jakości

forma przeciwciała

purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

1C9.1, monoclonal

reaktywność gatunkowa

human, rat

metody

immunohistochemistry: suitable
western blot: suitable

izotyp

IgG2aκ

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... NLGN1(22871)

Opis ogólny

Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.

Immunogen

Epitope: Extracellular domain
GST-tagged recombinant protein corresponding to the extracellular domain of Human Neuroligin-1.

Zastosowanie

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroligin-1 in human cerebral cortex, rat cerebellum and rat cerebral cortex tissue.
Research Category
Neuroscience

Neuroscience
Research Sub Category
Synapse & Synaptic Biology

Growth Cones & Axon Guidance
This Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.

Jakość

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroligin-1 in 10 µg of rat brain tissue lysate.

Opis wartości docelowych

~94 kDa observed

Postać fizyczna

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Inne uwagi

Concentration: Please refer to lot specific datasheet.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Odwiedź Bibliotekę dokumentów

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