This product is carrier-free and does not contain glycerol, gelatin, or serum albumin. The antibody has not been tested for the suitability in Hyperion imaging application. The end-user will have to determine the suitability.
MABC539
Anti-SFRP2 Antibody, clone 80.8.6, azide free
clone 80.8.6, from mouse
Synonim(y):
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μg | Przewidywany termin wysyłki13 maja 2026zKuehne + Nagel Sp. z o.o. | 2060,00 zł |
Informacje o tej pozycji
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
80.8.6, monoclonal
Application:
IHC, inhibition assay
Citations:
3
Pomoc techniczna
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Pozwól nam pomócQuality Level
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
80.8.6, monoclonal
species reactivity
human
technique(s)
immunohistochemistry: suitable, inhibition assay: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SFRP2(6423)
General description
Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 (SFRP2) may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. SFRP2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury.
33 kDa calculated
Immunogen
Epitope: NTR domain
Linear peptide corresponding to the NTR domain of human SFRP2.
Application
Anti-SFRP2 Antibody, clone 80.8.6, azide free is an antibody against SFRP2 for use in IHC & inhibition.
Inhibition Assay Analysis: Anti-SFRP2, clone 80.8.6 inhibits tube formation and cell migration in vitro on SVR angiosarcoma cells, inhibits angiosarcoma and breast cancer growth in vivo, and increases nuclear NFATc3 levels.
Physical form
Format: Purified
Analysis Note
Evaluated by Immunohistochemistry in human prostate and human breast cancer tissue.
Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected SFRP2 in human prostate and human breast cancer tissue.
Imunnohistochemistry Analysis: A 1:500 dilution of this antibody detected SFRP2 in human prostate and human breast cancer tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Ta pozycja | |||
|---|---|---|---|
| species reactivity human | species reactivity rat, mouse, human | species reactivity mouse, human, bovine | species reactivity mouse, human, guinea pig, horse, dog, rat |
| clone 80.8.6, monoclonal | clone polyclonal | clone polyclonal | clone polyclonal |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| antibody form purified antibody | antibody form affinity isolated antibody | antibody form affinity isolated antibody | antibody form IgG fraction of antiserum |
| Gene Information human ... SFRP2(6423) | Gene Information human ... SFRP2(6423) | Gene Information human ... SFRP1(6422) | Gene Information human ... SFRP1(6422) |
| biological source mouse | biological source rabbit | biological source goat | biological source rabbit |
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MABC539 | 04053252955884 |
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Our department is interested in your anti-SFRP antibody (MABC539). We would like to use it for Hyperion imaging. Hence, the antibody has to be glycerol free, BSA free, gelatine free, carrier free and unconjugated. Is the antibody presented in 100% PBS?
1 answer-
Helpful?
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