GF166
BMP-2 Protein, Human Recombinant
The Human Bone morphogenetic protein 2 (or BMP-2 protein) is a member of the BMP protein subgroup of the TGFβ superfamily.
Synonim(y):
Bone Morphogenetic Protein 2, BMP2, BMP-2A
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wybierz wielkość
10 μG
1690,00 zł
Wybierz wielkość
Zmień widok
10 μG
1690,00 zł
About This Item
Kod UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.77
Polecane produkty
Opis ogólny
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGFβ superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant human BMP-2 is a 26.0 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.
Product Source: E. coli.
Specyficzność
Cross Reactivty
Mouse, Rat, Rabbit, Cow, Dog, Monkey
Mouse, Rat, Rabbit, Cow, Dog, Monkey
Zastosowanie
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Jakość
Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
Postać fizyczna
Product is filtered through a 0.2 micron filter before lyophilization.
Przechowywanie i stabilność
Store at -20°C for up to 6 months from date of receipt.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Ta strona może zawierać tekst przetłumaczony maszynowo.
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Klienci oglądali również te produkty
Xingtao Ge et al.
American journal of translational research, 13(6), 6330-6341 (2021-07-27)
To investigate the protective effects of Naringin on glucocorticoid-induced osteoporosis (GIOP) through the PI3K/AKT/mTOR signaling pathway in vivo and in vitro. Osteoblasts were cultured from the differentiated bone marrow mesenchymal stem cells (BM-MSCs) and were grouped as follows: the PBS
Active Filters
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
Skontaktuj się z zespołem ds. pomocy technicznej
