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Merck

AB5204

Anti-Sodium Channel Antibody, Voltage Gated, Brain Type I

Chemicon®, from rabbit

Synonim(y):

Nav1.1, SCN1A

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Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
11
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SCN1A(6323)

Immunogen

Purified peptide from 465-481 of alpha subunit of rat type I voltage-gated sodium channel (VGSC) (Accession P04774).

Application

All procedures that are going to receive a full-length protein should be performed at 4C, and the following protease inhibitor mixture should be used: pepstatin A (1 μg/mL), leupeptin (1 μg/mL), aprotinin (1 μg/mL), Pefabloc SC (0.2 mM), benzamidine (0.1 mg/mL), and calpain inhibitors I and II (8 μg/mL each).

Western blot: 1:200 using ECL on rat brain membranes.

Immunohistochemistry on rat brain fixed frozen sections and mouse heart tissue.

Dilutions should be made using a carrier protein such as BSA (1-3%)

Optimal working dilutions must be determined by the end user.
This Anti-Sodium Channel Antibody, Voltage Gated, Brain Type I is validated for use in IH, WB for the detection of Sodium Channel.

Biochem/physiol Actions

Recognizes type I alpha subunit of VGSC. Does not cross react with any other sodium channel antigens tested so far.

SPECIES REACTIVITIES: It is expected that the antibody may also react with human due to sequence homology. Other species have not been tested.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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hcodes

Hazard Classifications

Aquatic Chronic 3

Klasa składowania

11 - Combustible Solids

wgk

WGK 3



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Numer pozycji handlu globalnego

SKUNUMER GTIN
AB520404053252323881
AB5204-50UL04053252334955