8.07491

Polyethylene glycol

6000, for synthesis

• Synonim(y): Poly(ethylene glycol), Polyethylene glycol 6000, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 6000, PEG
• Wzór liniowy: H(OCH₂CH₂)_nOH
• Numer CAS: 25322-68-3
• Numer MDL: MFCD00081839
• Kod UNSPSC: 13111021
• Numer indeksu EC: 500-038-2
• NACRES: NA.22

Właściwości

• ciśnienie pary: <0.01 hPa ( 20 °C)
• Poziom jakości: 200
• Postać: solid
• temp. samozapłonu: 420 °C
• siła działania: 28000 mg/kg LD₅₀, oral (Rat); >20000 mg/kg LD₅₀, skin (Rabbit)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• mp: 58-63 °C
• temp. przejścia: flash point 270 °C
• gęstość: 1.2 g/cm³ at 20 °C
• temp. przechowywania: 2-30°C
• ciąg SMILES: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• Klucz InChI: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Opis

Opis ogólny

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Zastosowanie

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-A_l2O₃. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size. It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule. PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.

Komentarz do analizy

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 281.5 °F - closed cup
• Temperatura zapłonu (°C): 138.6 °C - closed cup