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178385

Apocynin

≥98% (GC), powder, NADPH oxidase inhibitor, Calbiochem®

Synonim(y):

4-hydroksy-3-metoksyacetofenon, acetowanilon, inhibitor oksydazy NADPH V, inhibitor NOX V

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Gabaryty przesyłkiSKUDostępnośćCena netto
1 g

Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o.

576,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C9H10O3
Numer CAS:
498-02-2
Masa cząsteczkowa:
166.17
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD00008747
Assay:
≥98% (GC)
Form:
powder
Quality level:
100
Storage condition:
OK to freeze, protect from light

576,00 zł

Dostępne do wysyłki DZISIAJSzczegóły

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Nazwa produktu

Apocynin, A cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase.

Quality Level

100

description

Merck USA index - 14, 741

assay

≥98% (GC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

off-white to brown

solubility

DMSO: 10 mg/mL, ethanol: 20 mg/mL

shipped in

ambient

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Ta pozycja
PHL83252A10809W508454
Apocynin A cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase.

Sigma-Aldrich

178385

Apocynin

Apocynin phyproof® Reference Substance

PHL83252

Apocynin

4′-Hydroxy-3′-methoxyacetophenone 98%

Sigma-Aldrich

A10809

4′-Hydroxy-3′-methoxyacetophenone

Acetovanillone ≥98%, FG

Sigma-Aldrich

W508454

Acetovanillone

form

powder

form

solid

form

powder

form

-

assay

≥98% (GC)

assay

≥95.0% (HPLC)

assay

98%

assay

≥98%

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

300

manufacturer/tradename

Calbiochem®

manufacturer/tradename

PhytoLab

manufacturer/tradename

-

manufacturer/tradename

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

DMSO: 10 mg/mL, ethanol: 20 mg/mL

solubility

-

solubility

-

solubility

-

General description

A cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase. Shown to block peroxynitrite formation in murine macrophages. Reported to increase glutathione synthesis through activation of AP-1. Also reported to prevent phagocytosis of myelin by macrophages (10 mM).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
NADPH oxidase
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Abid, M.R., et al. 2000. FEBS Lett.486, 252.
Muijsers, R.B., et al. 2000. Br. J. Pharmacol.130, 932.
Lapperre, T.S., et al. 1999. FEBS Lett.443, 235.
Supinski, G., et al. 1999, J. Appl. Physiol.87, 776.
van der Goes, A., et al. 1998. J. Neuroimmunol.92, 67.
Hart, B.A., and Simmons, J.M. 1992. Biotechnol. Ther.3, 3.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)
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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Klasa składowania

11 - Combustible Solids

wgk

WGK 2

Certyfikaty analizy (CoA)

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SKUNUMER GTIN
178385-1GM04055977222463

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