L-029

Lacosamide solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Wzór empiryczny (zapis Hilla): C₁₃H₁₈N₂O₃
• Numer CAS: 175481-36-4
• Masa cząsteczkowa: 250.29
• Numer MDL: MFCD08272557
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329817347
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Postać: liquid
• Właściwości: Snap-N-Spike^®/Snap-N-Shoot^®
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• stężenie: 1.0 mg/mL in acetonitrile
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: clinical testing
• format: single component solution
• temp. przechowywania: −20°C
• ciąg SMILES: CC(N[C@H](COC)C(NCC1=CC=CC=C1)=O)=O
• InChI: 1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
• Klucz InChI: VPPJLAIAVCUEMN-GFCCVEGCSA-N
• informacje o genach: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Opis

Opis ogólny

A Certified Spiking Solution^® suitable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, prescription monitoring or pharmaceutical research. Lacosamide is a new antiepileptic drug developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. The drug is marketed under the trade name Vimpat^®.

Zastosowanie

• Lacosamide solution as a mass spectrometry standard: A recent development in analytical techniques features a UPLC-MS/MS method for determining lacosamide and its metabolites, essential for drug-drug interaction studies. This research underlines lacosamide′s role as a critical pharmaceutical research tool in the study of anti-epileptic drugs and their interactions (Chen et al., 2023).


• Lacosamide as an anticonvulsant in pharmacological research: Investigations on the effects of chronic lacosamide on ovarian tissue in rats highlight the broader physiological impacts of long-term anti-seizure medication use. Such studies are critical for assessing the reproductive safety of anticonvulsants, informing guidelines for their use in women of childbearing age (Kart et al., 2022).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vimpat is a registered trademark of Harris FRC Corporation

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H302 + H312 + H332,H319
• Zwroty wskazujące środki ostrożności: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 35.6 °F - closed cup
• Temperatura zapłonu (°C): 2 °C - closed cup