D-061

11-Deoxycortisol solution

Name: 11-Deoxycortisol solution
Brand: CERILLIAN
Price: 614 PLN

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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1 ML

614,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₂₁H₃₀O₄

Numer CAS:

152-58-9

Masa cząsteczkowa:

346.46

NACRES:

NA.24

PubChem Substance ID:

329798624

UNSPSC Code:

41116107

EC Number:

200-659-6

MDL number:

MFCD00003662

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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

InChI key

WHBHBVVOGNECLV-OBQKJFGGSA-N

Powiązane kategorie

Biomarker & Metabolite Standards

Certified Reference Materials

Controlled Substances & Illicit Drug Standards

General description

A new calibration material suitable for multiple LC/MS applications in clinical and diagnostic testing and endocrinology. An immediate precursor to cortisol, 11-deoxycortisol, or cortodoxone, is measured in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, pituitary tumor, and Addison′s disease.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P260 - P280 - P301 + P310 - P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Klasa składowania

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Wykazy regulacyjne

Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.

67-56-1

CAS No.

rmu

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Changes in steroid concentrations with the timing of corticotropin stimulation testing in participants with adrenal sufficiency.

Jacqueline Jonklaas et al.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 18(1), 66-75 (2011-08-23)

To determine whether the time of day at which corticotropin stimulation testing is performed influences the steroid concentrations observed in persons with normal adrenal function. In this retrospective, secondary analysis, participants with normal adrenal function were studied to determine whether

Lamprey endocrinology is not ancestral.

Joseph W Thornton et al.

Proceedings of the National Academy of Sciences of the United States of America, 108(2), E5-E5 (2011-01-07)

Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxycortisol with ultra high performance liquid chromatography-tandem mass spectrometry: Application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory.

Brett C McWhinney et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2863-2869 (2010-09-21)

We describe an ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC MS/MS) method suitable for a routine laboratory to determine endogenous and exogenous glucocorticoids in plasma, plasma ultrafiltrate, urine and saliva in a single analytical run. After addition of a

3D models of lamprey corticoid receptor complexed with 11-deoxycortisol and deoxycorticosterone.

Michael E Baker et al.

Steroids, 76(13), 1451-1457 (2011-08-16)

The serum of Atlantic sea lamprey, a basal vertebrate, contains two corticosteroids, 11-deoxycortisol and deoxycorticosterone. Only 11-deoxycortisol has high affinity [K(d) ~ 3 nM] for the corticoid receptor [CR] in lamprey gill cytosol. To investigate the binding of 11-deoxycortisol to

Progestin signaling through mPRα in Atlantic croaker granulosa/theca cell cocultures and its involvement in progestin inhibition of apoptosis.

Gwen E Dressing et al.

Endocrinology, 151(12), 5916-5926 (2010-10-22)

Although there is substantial evidence that membrane progestin receptors (mPRs) perform a critical physiological role in meiotic maturation of fish oocytes, it is unknown whether they are also intermediaries in progestin signaling in the surrounding follicular cells. Here, we show

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SKU	NUMER GTIN
D-061-1ML	04061833556689

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