A-158

Amoxapine-D₈ solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Wzór empiryczny (zapis Hilla): C₁₇H₈D₈ClN₃O
• Numer CAS: 1189671-27-9
• Masa cząsteczkowa: 321.83
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Poziom jakości: 300
• Postać: liquid
• Właściwości: Snap-N-Spike^®/Snap-N-Shoot^®
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• stężenie: 100 μg/mL in methanol
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: clinical testing
• format: single component solution
• temp. przechowywania: −20°C
• InChI: 1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2/i7D2,8D2,9D2,10D2
• Klucz InChI: QWGDMFLQWFTERH-UFBJYANTSA-N

Opis

Opis ogólny

This stable-labeled internal standard is suitable for quantification of amoxopine by LC-MS/MS or GC/MS for applications in clinical toxicology, forensic analysis, urine drug testing, pharmaceutical research, or therapeutic drug monitoring. Amoxopine is a tetracyclic antidepressant sold under notable trade names including Asendin^;, Asendis^;, Defanyl^; and Demolox^; for the treatment of major depressive disorder.

Zastosowanie

• Amoxapine-D8 internal standard: Utilization of Amoxapine-D8 as an internal standard in mass spectrometry significantly enhances analytical accuracy, particularly in bioanalytical assays aimed at understanding the pharmacokinetics and metabolite profiling of Amoxapine. This application is essential for ensuring precise measurement in pharmaceutical research (Lin H et al., 2024).
• Stable isotope-labeled Amoxapine for biochemical studies: The use of stable isotope-labeled Amoxapine-D8 enables detailed studies on its metabolism and interaction with biological systems. This approach is crucial for developing a deeper understanding of its biochemical pathways and potential therapeutic effects (Al-Fakhrany OM et al., 2024).
• Amoxapine-D8 in pharmacological research: Research involving Amoxapine-D8 explores its pharmacological actions, especially its utility in treating conditions like depression and anxiety. By using deuterated versions, researchers can gain insights into the drug′s behavior in the body, improving the development of effective therapeutic regimens (Ainousah BE et al., 2024).
• High-purity Amoxapine-D8 for mass spectrometry: High-purity Amoxapine-D8 is critical for mass spectrometry applications where accuracy and minimal background noise are paramount. This purity level facilitates the study of complex biological samples, enabling more precise and reliable analytical outcomes (Sharma MK et al., 2024).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H301 + H311 + H331,H370
• Zwroty wskazujące środki ostrożności: P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235
• Klasyfikacja zagrożeń: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Kod klasy składowania: 3 - Flammable liquids
• Temperatura zapłonu (°F): 49.5 °F - closed cup
• Temperatura zapłonu (°C): 9.7 °C - closed cup