83060

tert-Butyl 12-amino-4,7,10-trioxadodecanoate

technical, ≥80% (T)

• Synonim(y): Amino-PEG3-tert-butyl ester, tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate
• Wzór empiryczny (zapis Hilla): C₁₃H₂₇NO₅
• Numer CAS: 252881-74-6
• Masa cząsteczkowa: 277.36
• NACRES: NA.22
• PubChem Substance ID: 57652942
• UNSPSC Code: 12352200
• MDL number: MFCD06201017
• Assay: ≥80% (T)
• Form: solid

Właściwości

• grade: technical
• Quality Segment: 100
• assay: ≥80% (T)
• form: solid
• reaction suitability: reagent type: cross-linking reagent
• storage temp.: −20°C
• SMILES string: CC(C)(C)OC(=O)CCOCCOCCOCCN
• InChI: 1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3
• InChI key: CWFSAZJIJBTKRC-UHFFFAOYSA-N

Opis

Application

tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:

• Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
• Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
• Synthesis of polycationic adamantane-based dendrons for cell imaging.
• Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).

Other Notes

Intermediate in the synthesis of a spacer for combinatorial chemistry

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: 337.5 °F
• flash_point_c: 169.7 °C
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter