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PRKCE

protein kinase C, epsilon

Synonimy:
PKCE, nPKC-epsilon
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
  • Mouse(18754) protein kinase C, epsilon
  • Rat(29340) protein kinase C, epsilon
  • chicken(421409) protein kinase C, epsilon
  • domestic cat(101100958) protein kinase C, epsilon
  • dog(609934) protein kinase C, epsilon
  • cow(507041) protein kinase C, epsilon
  • Horse(100053394) protein kinase C, epsilon
  • Domestic Rabbit(100009103) protein kinase C, epsilon
  • sheep(101110314) protein kinase C, epsilon
  • naked mole-rat(101700837) protein kinase C, epsilon
  • domestic guinea pig(100721814) protein kinase C, epsilon

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Oleic acid, ≥99% (GC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PKC ε antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-PKC epsilon Antibody, clone 8I8K4, Rabbit Monoclonal, ,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
H-7 dihydrochloride, ≥98% (HPLC),
Gatunek
human
Tamoxifen citrate salt, ≥99%,
Gatunek
human
Oleic acid, ≥99% (GC),
Gatunek
human
UCN-01, ≥97% (HPLC), powder,
Gatunek
human
GSK690693, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
PKC ε , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
PKCε Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end. For use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PRKCE,
Gatunek
human
MISSION® esiRNA, targeting mouse Prkce,
Gatunek
mouse