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Merck

NDUFA5

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5

Synonimy:
B13, CI-13KD-B, CI-13kB, NUFM, UQOR13
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4698) Summary: The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq, Jul 2008]
  • Mouse(68202) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • Rat(25488) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 5
  • naked mole-rat(101701548) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • domestic guinea pig(100723200) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • domestic cat(101092508) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • cow(327714) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • sheep(101123463) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • Zebrafish(541328) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
  • chicken(417753) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa
  • dog(475214) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-NDUFA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-NDUFA5wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
1,1-Dimethylbiguanide hydrochloride, 97%,
Gatunek
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Metformina, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human NDUFA5 (2),
Gatunek
human
MISSION® esiRNA, targeting human NDUFA5 (1),
Gatunek
human
MISSION® esiRNA, targeting mouse Ndufa5,
Gatunek
mouse